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KMID : 0380519990030010055
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Korean Journal of Veterinary Pathology
1999 Volume.3 No. 1 p.55 ~ p.59
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Squamous Cell Carcinoma in Pere David Deer
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Woo Gae-Hyeong
Seo Il-Bok
Kim Jae-Hoon
Kweon Oh-Kyeong
Shin Nam-Sik
Kwon Soo-Wahn
Kim Dae-Yong
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Abstract
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Metastatic squamous cell carcinoma was described in two female Pere David’s deer reared at Everland zoo. Both deer with chronic emaciation had the mass on right maxilla(91115cm or 2017cm) which was composed of miliary tan creamy contents and encapsulated by connective tissue. The undulating contents in the mass was a1so extended in the underlying or adjacent soft palate, maxillary and frontal sinus causing severe bone destruction. In one deer, two fistula were also noted in the right periocular area. Histologically, the neoplastic masses of both deer consist of anastomosing cords or nests of squamous epithelial cells with intercellular bridge or keratin pearl formation. The neoplastic cells invade deep into the subcutis and bony tissue. Mitotic figure was rare. Multifocal areas of necrosis and hemorrhages were also noted in the dermis. Metastasis to maxilla and ethmoid bones and/or to submandibular lymph node was noted in both cases. The diagnosis was based on the results of histopathology.
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KEYWORD
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Pere David′s Deer, Elaphurus davidianus, squamous cell carcinoma, neoplasia
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